Acne Spot Treatments: Effective Anti-inflammatory and Swelling Reduction for Pustules, Papules, and Inflamed Acne with Salicylic Acid, Benzoyl Peroxide, AHA, and Tea Tree Oil. AVAKids explores the top 12 best acne spot treatments for women!
1What are Acne Spot Treatments?
Acne spot treatments are specialized products designed to treat acne. They possess strong antibacterial properties and the ability to quickly reduce swelling and inflammation, minimizing the spread and preventing the acne from worsening. Additionally, they help prevent acne-causing agents and skin infections.

Acne spot treatments are specialized products for treating acne.
2Active Ingredients in Acne Spot Treatments
- Salicylic Acid: This acne-fighting ingredient is primarily used to treat various skin disorders such as acne, dandruff, psoriasis, seborrheic dermatitis on the skin or scalp, calluses, warts, and corns.
- Benzoyl Peroxide: A specialized ingredient for treating acne, benzoyl peroxide helps reduce the number of germs and bacteria on the skin’s surface. Products containing benzoyl peroxide are often available in gel or face wash form. This ingredient can be purchased at pharmacies under the brand name Acnecide.
- AHA: AHA is a type of fruit-derived acid commonly used as a skin exfoliant. It improves skin texture, fades dark spots, and reduces signs of aging. However, AHA can increase skin sensitivity to UV rays, so don’t forget to use sunscreen!
- Tea Tree Oil: Considered an “archenemy” of acne, tea tree oil is believed to have similar effects to benzoyl peroxide, protecting the skin from acne-causing agents.

Active ingredients in acne spot treatments help reduce inflammation and redness.
3Criteria for Choosing Safe and Effective Acne Spot Treatments
3.1. Antibacterial Properties
Antibacterial action is a top priority, as sebum and dirt on the skin can clog pores, leading to bacterial growth and severe acne. Therefore, choose a product with good antibacterial properties for spot treatment.
3.2. Effective Dark Spot Reduction
After eliminating stubborn acne, dark spots can be a challenging issue. Therefore, spot treatments that both treat acne and fade post-acne marks are the optimal choice.

Choose an acne spot treatment with good dark spot reduction capabilities.
3.3. Ingredients
Recommended ingredients for acne spot treatments include Isopropyl methylphenol, sulfur, triclosan, and resorcinol. If you have sensitive or easily irritated skin, natural and gentle products are the best choice.

Some By Mi AHA-BHA-PHA 30 Days Miracle Acne Treatment Cream 60g
3.4. Reputable Brand
Many counterfeit and unverified cosmetic products are on the market. Prioritize well-known and established brands like La Roche Posay, Some By Mi, and purchase from reputable stores.
4Top 12 Best Acne Spot Treatments for Reducing Swelling and Fighting Bacteria
4.1. Neogen Dermalogy Double Action Spot Treatment
- Brand: Neogen
- Origin: South Korea
- Volume: 15ml
- Reference Price: Approximately 350,000VNĐ (Updated June 2023)
Neogen is a renowned skincare brand that has earned widespread trust. One of its most distinctive features is the application of the exclusive “NEOGEN NATURALS – six-core biotechnology,” which maximizes the benefits of natural ingredients.
Key Features:
- Contains sulfur to soothe inflamed acne.
- Salicylic acid cleanses and unclogs pores.
- Effective on red, inflamed areas and severe cystic acne.

Neogen Dermalogy Double Action Spot Treatment
4.2. Obagi CLENZIderm Therapeutic Lotion
- Brand: Obagi
- Origin: USA
- Volume: 10ml or 47ml
- Reference Price: 490,000 – 2,000,000VNĐ (Updated June 2023)
Obagi is a pioneering brand in the cosmeceutical market and has been voted the world’s best physical skincare brand. Obagi is well-known for its Obagi CLENZIderm Therapeutic acne treatment.
Key Features:
- Contains 5% Benzoyl Peroxide to eliminate bacteria and cleanse pores.
- Includes Squalane to moisturize, nourish, and prevent dry skin.
- Exfoliates pore-clogging dead skin cells.

Obagi CLENZIderm Therapeutic Lotion
4.3. La Roche-Posay Effaclar Duo+
- Brand: La Roche-Posay
- Origin: France
- Volume: 40ml
- Reference Price: Approximately 400,000VNĐ (Updated June 2023)
Alongside Obagi, La Roche Posay is another “heavy hitter” in the cosmeceutical market. This brand is recognized and recommended by over 90,000 dermatologists worldwide, with many high-quality product lines like skincare creams, moisturizers, and acne treatments. La Roche Posay Effaclar Duo+ is effective and suitable even for the most sensitive skin.
Key Features:
- Niacinamide for sensitive skin reduces redness and itching, restores the skin barrier, and soothes the skin.
- Contains Aqua Posae Prebiotic: Balances the skin’s microbiome and enhances regeneration for faster acne reduction.
- Aqua Posae Filiformis balances the skin’s microbiome, reduces swelling, prevents acne recurrence, and inhibits the activity of harmful bacteria.
- Gel texture absorbs quickly and doesn’t leave a sticky or greasy residue.

La Roche-Posay Effaclar Duo+
4.4. Klenzit C
- Brand: Glenmark Pharmaceuticals LTD
- Origin: India
- Volume: 15g
- Reference Price: Approximately 200,000VNĐ (Updated June 2023)
Klenzit C, by Glenmark Pharmaceuticals LTD, is commonly used in dermatology clinics for effectively treating inflamed acne. Klenzit C is currently distributed and officially sold in Vietnam by Hanoi Pharmaceutical and Medical Equipment Joint Stock Company.
Key Features:
- Transparent gel formula absorbs quickly without leaving a greasy or sticky residue.
- Clindamycin as the main ingredient inhibits bacterial activity and reduces sebum production.
- Purges acne and unclogs pores.

Klenzit C Acne Spot Treatment
4.5. Epiduo Acne Treatment Gel
- Brand: Galderma Laboratories
- Origin: France
- Volume: 15g, 30g, and 45g
- Reference Price: 200,000 – 420,000VNĐ (Updated June 2023)
Epiduo Gel by Galderma Laboratories is a specialized product for acne-prone skin, especially cystic acne, inflamed acne, or conditions like hidden acne, clogged pores, and sebaceous filaments. Applying Epiduo Gel directly to affected areas daily can quickly improve these conditions.
Key Features:
- Gel formula suitable for acne-prone and sensitive skin.
- Uses adapalene and benzoyl peroxide, medications used to treat acne.
- Simultaneously targets acne-causing agents, accelerating treatment time.

Epiduo Acne Treatment Gel
4.6. Some By Mi Super Miracle Spot All Kill Cream
- Brand: Some By Mi
- Origin: South Korea
- Volume: 30ml
- Reference Price: Approximately 350,000VNĐ (Updated June 2023)
Some By Mi is a well-known skincare brand that utilizes tea tree extract. Their products are particularly effective in addressing skin problems, especially hidden acne, inflamed acne, swollen acne, and cystic acne.
Key Features:
- Proprietary True Cica 750,000ppm (75%) complex, including centella asiatica extract, mugwort extract, and tea tree extract, reduces swelling and inflammation.
- Contains AHA, BHA, and PHA 900ppm to exfoliate dead skin cells and unclog pores.
- Helps treat and prevent new acne formation, suitable even for sensitive skin.

Some By Mi Super Miracle Spot All Kill Cream
4.7. Derma Forte
- Brand: Gamma
- Origin: Vietnam
- Volume: 15g
- Reference Price: Approximately 110,000VNĐ (Updated June 2023)
Derma Forte is a product of Gamma, a company specializing in cosmetics, from shampoos and body washes to skincare products. This acne spot treatment is well-received not only in Vietnam but also in many countries worldwide.
Key Features:
- Treats various types of acne, including blackheads, inflamed acne, whiteheads, swollen acne, and painful acne.
- Helps heal scars, prevents acne recurrence, and reduces skin aging.
- Helps fade dark spots during acne treatment.

Derma Forte Acne Spot Treatment
4.8. Paula’s Choice 2.5% Benzoyl Peroxide
- Brand: Paula’s Choice
- Origin: USA
- Volume: 67ml
- Reference Price: 550,000 – 600,000 VNĐ (Updated June 2023)
Paula’s Choice is a familiar and trusted brand, effective for acne-prone skin or those with other skin concerns. The brand is widely recognized worldwide for its products containing BHA, AHA, Benzoyl Peroxide, and other antioxidants.
Key Features:
- Salicylic acid removes oil and sebaceous filaments, exfoliating the skin.
- Unclogs pores and reduces inflammation.
- Soothes skin, stimulates new skin regeneration, and minimizes scarring.

Paula’s Choice 2.5% Benzoyl Peroxide Acne Spot Treatment
4.9. Hiruscar Anti-Acne Gel
- Brand: Hiruscar
- Origin: Switzerland
- Volume: 10g
- Reference Price: Approximately 140,000 VNĐ (Updated June 2023)
Hiruscar is a preferred brand for its highly effective products. Its Anti-Acne Gel is highly regarded for its superior acne treatment and swelling reduction.
Key Features:
- Gel formula absorbs quickly without leaving a sticky residue.
- Vitamin C promotes collagen production and provides essential antioxidant protection.
- Contains BHA for gentle exfoliation, reducing pore-clogging, a major cause of acne.

Hiruscar Anti-Acne Gel
4.10. Naruko Tea Tree Acne Spot Serum
- Brand: Naruko
- Origin: Taiwan
- Volume: 30ml
- Reference Price: 250,000 – 290,000 VNĐ (Updated June 2023)
Naruko is a well-known cosmetics brand. Naruko products are primarily made from 100% Taiwanese plants such as red coix seed, white magnolia, and especially tea tree oil, which is highly effective in fighting bacteria and reducing swelling and inflammation.
Key Features:
- Reduces inflammation, exfoliates, unclogs pores, and prevents blockage.
- Treats and prevents the development and spread of acne.
- Reduces excess oil, sebum, and bacteria, contributing to the treatment of other skin problems.

Naruko Tea Tree Acne Spot Treatment
4.11. Some By Mi AHA-BHA-PHA 30 Days Miracle Serum
- Brand: Some By Mi
- Origin: South Korea
- Volume: 50ml
- Reference Price: Approximately 311,500 – 445,000VNĐ (Updated June 2023)
Some By Mi cosmetics is famous for its safe and natural ingredients. The brand’s products have a mild or even no scent due to the absence of fragrances, resulting in high effectiveness in treating inflamed and hidden acne.
Key Features:
- Removes dead skin cells, balances excess oil, improves inflamed and hidden acne, and prevents acne-causing bacteria.
- The dual-layered, lightweight texture enhances moisturizing effects while absorbing quickly without leaving a sticky residue.
- Soothes irritated skin and reduces redness, moisturizes, and controls sebum.
- Has antibacterial, anti-inflammatory, and acne-preventing properties.

Some By Mi AHA-BHA-PHA 30 Days Miracle Serum
4.12. Vichy Normaderm Phytosolution Double-Correction Daily Care
- Brand: Vichy
- Origin: France
- Volume: 50ml
- Reference Price: Approximately 406,000 – 580,000VNĐ (Updated June 2023)
Vichy is a premium French cosmetics brand established in 1931 and is now widely available globally. Vichy products are manufactured in a safe environment and deliver high-quality beauty results. Vichy’s acne treatment gel is renowned for its effective treatment of acne and dark spots.
Key Features:
- Designed specifically for oily and acne-prone skin, providing a dual action that reduces acne, improves skin imperfections, and strengthens the skin barrier.
- Provides 15 essential minerals the body can’t produce on its own, improving the skin barrier daily for healthier skin and reduced irritation from external factors.
- Anti-inflammatory, releases excess oil from deep within pores, regulates sebum, and reduces oiliness.
- Contains vitamin C for antioxidant protection, evens skin tone, and improves dark spots.
- Lightweight gel-milk texture absorbs quickly without leaving a greasy residue, providing a refreshing sensation.

Vichy Normaderm Phytosolution Double-Correction Daily Care
5Precautions When Using Acne Spot Treatments
For optimal results when using acne spot treatments, keep the following in mind:
- Limit the use of strong active ingredients: Avoid using other strong active ingredients before applying spot treatment if your skin is sensitive.
- Apply a lightweight gel serum or moisturizer: This can be done before or after applying the spot treatment depending on your skin condition. For thin, red, and easily irritated skin, apply serum/moisturizer before spot treatment. Reverse the order for healthier skin.
- Use regularly for best results: Start with a low frequency (every other day) to allow your skin to adjust, then gradually increase to daily use.
- Usage and storage: Use the product according to the manufacturer’s instructions or as directed by a specialist. Store the product in a cool, dry place away from direct sunlight.

Use acne spot treatment regularly for best results.
6Frequently Asked Questions About Acne Spot Treatments
6.1. Should I apply spot treatment before or after moisturizer?
Whether you apply spot treatment before or after moisturizer depends on your skin type. If your skin is thin, red, and easily irritated, apply moisturizer first, then spot treatment. Conversely, if your skin is healthier, you can apply spot treatment before moisturizer for best results.
6.2. Should I apply acne treatment before or after serum?
Similar to moisturizer, whether you apply spot treatment before or after serum depends on your skin condition. If your skin is thin and sensitive, apply serum first, then spot treatment. If you have healthier skin, you can apply spot treatment before serum for best results.

Whether you apply spot treatment before or after serum depends on your skin condition.
7Where to Buy Reputable and High-Quality Acne Spot Treatments
To avoid purchasing counterfeit or low-quality products, choose reputable and reliable retailers for your acne spot treatments. Currently, AVAKids stores officially distribute reputable acne spot treatment brands. You can purchase directly at the store or through the AVAKids website.
- Guaranteed 100% authentic products.
- Exchange for a new product or 100% refund within 7 days (applicable to products with defects caused by the manufacturer/retailer).
- Various delivery and payment methods.
- Support and consultation via hotline 1900.866.874 (8:00 – 21:30).
(The above policies were updated in June 2023 and are subject to change. You can view the latest information here).
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In this article, AVAKids has explored the 12 best acne spot treatments that help control acne, reduce inflammation, and fight bacteria. When choosing a spot treatment, prioritize products containing BHA or tea tree oil for optimal results. If you have any questions, please contact our hotline at 1900.866.894 or visit our website at avakids.com for the quickest assistance!